When Jamie Luth talks about generosity, she doesn’t start with numbers or fundraising goals. She starts with her husband, Ethan and a Christmas Eve that changed everything.

On December 24, 2025, while living just outside The Hague, Netherlands, the Luth family received devastating news: Ethan had pancreatic cancer. What began as months of unexplained back pain had escalated into a diagnosis that would upend their lives and send them racing for answers across continents.

Within weeks, the family made the difficult decision to return to St. Louis for care at Siteman Cancer Center, where Ethan entered a clinical trial, one of two currently underway showing promising results for pancreatic cancer treatment.

For Jamie, the diagnosis quickly became a call to action. Alongside her friend Kira Andersen, she began volunteering with the Pancreatic Cancer Research Fund at Siteman Cancer Center, supporting the “Turning Pain Into Purpose” initiative honoring Kira’s late husband, Kyle Andersen, whose legacy continues to inspire ongoing research efforts. Together, they are helping lead a national push to fund breakthroughs in pancreatic cancer treatment.

Since beginning in April, Jamie has dedicated several hours each day to raising awareness and supporting fundraising efforts. The mission is deeply personal: “This isn’t just about hope for the future,” she shares. “It’s about giving Ethan a chance to be here for our three daughters and helping ensure other families don’t have to go through this.”

The initiative has already helped raise $2 million toward pancreatic cancer research, with a goal of reaching $3 million to fully fund critical studies. These trials are not only advancing pancreatic cancer treatment but are also showing promise for liver, lung, and colorectal cancers.

For the Luth family, generosity now looks like action, sharing their story, building community support, and pushing forward research that could change survival outcomes for countless families.

“It’s overwhelming at times,” Jamie says, “but if our story can help move this forward even a little faster, then it’s worth every bit of it.”

For more information or to donate visit: siteman.donordrive.com/campaign/Ethan-and-Jamie-Luth